Cabozantinib (XL184)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
849217-68-1
BMS-907351
C16126-10mg
C-Met
Protein Tyrosine Kinase
COC1=CC2=C (C=CN=C2C=C1OC) OC3=CC=C (C=C3) NC (=O) C4 (CC4) C (=O) NC5=CC=C (C=C5) F
C28H24FN3O5
Cabozantinib (XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway.
2 years -80 in solvent
Beschrijving
Cabozantinib (XL184) Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 10 mg
10 mg
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
CSB-NP000101r-01
1 mg
Denhardt's Solution (50X)
EC-915
50 mL
FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
MBS623609-01
0.2 mL
West Nile Virus, NS3 Protease (WNV)
MBS603723-01
0.1 mg
Recent gezochte producten
BSA and BGG Stock standards (1 vial each @ 2 mg/ml) for BCA Optima Protein Assay kit
BSA-BGG-1
1 PK
General Bovine Serum Albumin (BSA) ELISA Kit
DL-BSA-Ge-01
48 Tests
General Bovine Serum Albumin (BSA) ELISA Kit
RD-BSA-Ge-01
96 Tests
Heparin
BSA-Hep-01 – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 50 mg
50 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 50 mg
50 mg