Cabozantinibhydrochloride
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1817759-42-4
XL184, BMS-907351 hydrochloride
C-Met
Protein Tyrosine Kinase
C28H24FN3O5.ClH
Cabozantinib hydrochloride (XL184, BMS-907351 hydrochloride) is a potent small-molecule kinase inhibitor of c-MET and VEGFR2 with an IC50 of 1.3 nM, 0.035 nM respectively. It also inhibits RET, KIT, AXL, Tie2 and FLT3 with an IC50's of 5.2 nM, 4.6 nM, 7 nM, 14.3 nM, 11.3nM respectively. It can be promising agent for inhibiting tumor angiogenesis and metastasis in cancers with dysregulated MET and VEGFR signaling.
Beschrijving
Cabozantinibhydrochloride Beschikbaar in 250 mg. Bestel eenvoudig online met snelle levering.
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