CAC / JNK (Ab 183) Antilichaam

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.

5601

P45984; ; ; P53779

NP_001128516.1

Human, Mouse, Rat

SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

46, 54 kDa

This antibody detects endogenous level of total SAPK/JNK protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

MAPK9

Mitogen-activated protein kinase 9

Homo sapiens

Ferrer, et al. (2003) Neuropathology & Applied Neurobiology 29: 23 Zhonghong Guan, et al. (1999) J Biol Chem, Vol. 274: 36200-36206D. Margriet Ouwens1, et al. (2002) The EMBO Journal 21: 3782–3793, S Matsuyoshi1, et al. (2006) British Journal of Cancer 94: 532

JNK2, SAPK, p54a, JNK2A, JNK2B, PRKM9, JNK-55, SAPK1a, JNK2BETA, p54aSAPK, JNK2ALPHA, CDHN, NCAD, JNK2

WB, IHC

205277412

Liquid