CACNA2D3 Antilichaam

CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.

55799

Q8IZS8

Q8IZS8

Human

This CACNA2D3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1026-1053 amino acids from the C-terminal region of human CACNA2D3.

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

123 kDa

Rabbit Ig

CACNA2D3

Voltage-dependent calcium channel subunit alpha-2/delta-3

Homo sapiens

Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)

Wanajo, A., et al. Gastroenterology 135 (2) :580-590 (2008)

Uhl, G.R., et al. Arch. Gen. Psychiatry 65 (6) :683-693 (2008)

Abo-Dalo, B., et al. Am. J. Med. Genet.143A (22), 2668-2674 (2007)

Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3, Voltage-dependent calcium channel subunit alpha-2-3, Voltage-dependent calcium channel subunit delta-3, CACNA2D3

WB, Flow

74723683

Liquid