CACNB2 Antilichaam - middengebied: Biotine (ARP35597 P050-Biotine)

Calcium channel, voltage-dependent, beta 2 subunit

CAB2, MYSB, CAVB2, CACNLB2

783

Q08289

NP_963884

Human, Mouse, Rat, Cow, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4) .

REM1; PRKACA

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

68kDa

Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693

Wet Ice

605

CACNB2

CACNB2

Rabbit

Voltage-dependent L-type calcium channel subunit beta-2

NM_201590

HLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGD

Beta-2