Calpain 9 (CAPN9) Mouse Monoclonal Antibody [Clone ID: LBI1C2]

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) CAPN9 mouse monoclonal antibody, clone LBI1C2

GC36; nCL-4

Homo sapiens calpain 9 (CAPN9), transcript variant 1, mRNA.

10753

O14815

Unconjugated

WB 1:2000, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CAPN9

https://www.ncbi.nlm.nih.gov/gene/?term=10753

https://www.uniprot.org/uniprot/O14815