CaMKII (fosfo Thr286) Antilichaam

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity .

12322

P11798

NP_001273738.1

Human, Mouse, Rat

CaMKII (Phospho-Thr286) antibody was raised against a peptide sequence around phosphorylation site of threonine 286 (Q-E-T (p) -V-D) derived from Human CaMKII.

Unconjugated

Primary Antibodies

Phospho-Specific, Neuroscience

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

50 kDa

This antibody detects endogenous level of CaMKII only when phosphorylated at threonine 286.

Western Blot: 1:500~1:1000

Camk2a

Calcium/calmodulin-dependent protein kinase II alpha

Homo sapiens

Pak JH, et al. Proc Natl Acad Sci U S A. 2000 Oct 10; 97 (21) : 11232-11237 Hudmon A, et al. J Cell Biol. Author manuscript; available in PMC 2006 May 7Miller P, et al. PLoS Biol. 2005 Apr; 3 (4) : e107Runyan JD, et al. Learn Mem. 2005 Mar; 12 (2) : 103-110.

CaMKII, R74975, mKIAA0968, FNRB, MDF2, MSK12, CAMK2A, CaMKII-alpha

WB

558472775

Liquid