Candidusine A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
81474-59-1
NF-κB, Apoptosis, AMPK, TNF
PI3K/Akt/mTOR signaling, NF-κB, Apoptosis, Chromatin/Epigenetic
Candidusin A (CHNQD-0803) (Compound 4) is an AMPK activator with a KD of 47.28 nM. This compound can be isolated from the marine fungus Aspergillus candidus. Candidusin A exhibits cytotoxic activity against human prostate cancer cells (22Rv1, PC-3, and LNCaP cells) and induces apoptosis. It reduces lipogenic gene expression and fat deposition, downregulates the NF-κB-TNFα inflammatory axis to suppress inflammation, and improves liver injury and fibrosis. Candidusin A is applicable in the study of non-alcoholic steatohepatitis (NASH) .
OC=1C=CC(=CC1)C2=CC(OC)=C3C(OC4=CC(O)=C(O)C=C43)=C2OC
C20H16O6
352.34
Ice Packs
-20°C
Beschrijving
Candidusine A Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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Hettich Centrifuge Rotanta 460R Refrigerated Large Volume
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X4RF Refrigerated Centrifuge
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Drug Stability Chamber
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Modular Incubator Chamber
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CYP707A2 Antibody
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SsDNA Assay Kit
12645ES60
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Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Recent gezochte producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
X4RF Refrigerated Centrifuge
75009936
1 Each
Low Speed Refrigerated Centrifuge
LX104LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX117LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX124LSR
1 Unit
Blood Bank Refrigerator
LX4000BBR
1 Unit
Blood Bank Refrigerator
LX4002BBR
1 Unit
Blood Bank Refrigerator
LX4003BBR
1 Unit