CAP-100
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CAP-100 is a monoclonal antibody that targets CCR7. CAP-100 neutralizes the ligand-binding site and signaling of CCR7. CAP-100 strongly inhibits CCR7-induced migration, extravasation, homing, and survival in chronic lymphocytic leukemia (CLL) samples. CAP-100 triggers potent tumor cell killing, mediated by host immune mechanism. CAP-100 shows a favorable toxicity profile on relevant hematopoietic subsets. CAP-100 is involved in research on anti-tumor and disease such as CLL[1].
12352203
CCR
GPCR/G Protein; Immunology/Inflammation
COVID-19-immunoregulation
Cancer; Inflammation/Immunology
99.84
[CAP-100]
(146.48 kDa)
[1]Cuesta-Mateos C, et al., Targeting cancer homing into the lymph node with a novel anti-CCR7 therapeutic antibody: the paradigm of CLL. MAbs. 2021 Jan-Dec;13 (1) :1917484.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991224/CAP-100-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 1
Beschrijving
CAP-100 is a monoclonal antibody that targets CCR7. CAP-100 neutralizes the ligand-binding site and signaling of CCR7. CAP-100 strongly inhibits CCR7-induced mi
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