Capmatinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1029712-80-8
INC280, NVP-INC280, INCB28060
C08858-10mg
C-Met
Protein Tyrosine Kinase
CNC (=O) C1=C (C=C (C=C1) C2=NN3C (=CN=C3N=C2) CC4=CC5=C (C=C4) N=CC=C5) F
C23H17FN6O
Capmatinib is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1.
2 years -80 in solvent
Beschrijving
Capmatinib Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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