CAPN3 Antilichaam

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A.

825

P20807

P20807

Human

This CAPN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-632 amino acids from the C-terminal region of human CAPN3.

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Batch dependent

Predicted species reactivity based on immunogen sequence: Monkey

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

94 kDa

Rabbit Ig

CAPN3

Calpain-3

Homo sapiens

Charlton, R., et al. Neuromuscul. Disord. 19 (7) :449-457 (2009)

Moretti, D., et al. Carcinogenesis 30 (6) :960-967 (2009)

Enjuanes, A., et al. Cancer Res. 68 (24) :10178-10186 (2008)

Beckmann, J.S., et al. Neuromuscul. Disord. 18 (12) :913-921 (2008)

Calpain-3, Calcium-activated neutral proteinase 3, CANP 3, Calpain L3, Calpain p94, Muscle-specific calcium-activated neutral protease 3, New calpain 1, nCL-1, CAPN3, CANP3, CANPL3, NCL1

WB, IHC-P, Flow

Liquid