CAPN9 Antilichaam

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

10753

O14815

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_006606.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

SGC-7901

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 79kDa

IgG

WB: 1:500 - 1:2000

CAPN9

HL-60

HT-29

Mouse stomach

Mouse small intestine

Rat stomach

Calpain-9

Homo sapiens

Calpain-9, 3422-, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36, CAPN9, NCL4

WB

Liquid