CAPZA3 Antilichaam - N-terminalgebied: HRP (ARP58604_P050-HRP)

Capping protein (actin filament) muscle Z-line, alpha 3

Gsg3, CAPPA3, HEL-S-86

93661

Q96KX2

NP_201585

Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human CAPZA3

F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.

UBC; CAPZA2; ACTG1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

33kDa

Miyagawa, Y., (2002) Mol. Hum. Reprod. 8 (6), 531-539

Wet Ice

299

CAPZA3

CAPZA3

Rabbit

F-actin-capping protein subunit alpha-3

NM_033328

MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGEC

Alpha-3