CAQ

CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635) . CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease[1].

12352005

Fluorescent Dye

Others

Neurological Disease

CN(C1=CC=C(C=C1)/C=C/C2=OB(F)(OC(/C=C/C3=CN=C4C=CC=CC4=C3)=C2)F)C

C24H21BF2N2O2

418.24

[1]Wu J, et al. InVivo Brain Imaging of Amyloid-β Aggregates in Alzheimer's Disease with a Near-Infrared Fluorescent Probe. ACS Sens. 2021 Mar 26;6 (3) :863-870.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-D2962/

Dye Reagents

No Development Reported