Carbutamide-d9

Carbutamide-d9 (BZ-55-d9) is the deuterium labeled Carbutamide. Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity[1].

1246820-50-7

BZ-55-d9

12352005

Isotope-Labeled Compounds

Others

Metabolic Disease

10 mM in DMSO

[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(NS(=O)(C1=CC=C(C=C1)N)=O)=O

C11H8D9N3O3S

280.39

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kleinsorge H, et al. Carbutamide--the first oral antidiabetic. A retrospect. Exp Clin Endocrinol Diabetes. 1998;106 (2) :149-51.|[3]ROOT MA, et al. Pharmacology of carbutamide (p-aminophenylsulfonyl butylcarbamide) . J Pharmacol Exp Ther. 1957 Apr;119 (4) :468-78.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W011651S/

Isotope-Labeled Compounds

No Development Reported