CARD17 Antilichaam - middengebied: Biotine (ARP61219 P050-Biotine)

Caspase recruitment domain family, member 17

INCA

440068

Q5XLA6

NP_001007233

Human

The immunogen is a synthetic peptide directed towards the middle region of human CARD17

As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.

CARD17; CARD16; CARD18; CASP1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

12kDa

Wet Ice

110

CARD17

CARD17

Rabbit

Caspase recruitment domain-containing protein 17

NM_001007232

MDKARALLDSVIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLT