CARD9 Antilichaam

CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κ B. CARD9 is an upstream activator of BCL-10 and NF-κ B signaling.

64170

Q9H257

AF311287

Human

Unconjugated

Primary Antibodies

Apoptosis

CARD9 Antibody is DEAE purified.

Cat. No. 1216 - PC-3 Cell Lysate

1 mg/ml

Predicted species reactivity based on immunogen sequence: Mouse: (88%), Rat: (82%)

CARD9 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CARD9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

59 kDa

IgG

CARD9

Cat. No. 1217 - MDA-MB-361 Cell Lysate

Cat. No. 1204 - K562 Cell Lysate

Cat. No. 17-004 - K-562 Cell Slide

Caspase recruitment domain family, member 9

Homo sapiens

Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-κ B. J Biol Chem. 2000;275 (52) :41082-6. (RD0202)

CARD9 Antibody: CANDF2, hCARD9, Caspase recruitment domain-containing protein 9

ELISA, WB, ICC

11066983

Liquid