Cardiale Troponine I (TNNC1) Muismonoklonale Antilichaam [Kloon ID: UMLBI204]

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

Carrier-free (BSA/glycerol-free) Troponin C (TNNC1) mouse monoclonal antibody, clone UMLBI204

CMD1Z; CMH13; TN-C; TNC; TNNC

Homo sapiens troponin C1, slow skeletal and cardiac type (TNNC1), mRNA.

7134

P63316

Unconjugated

Calcium signaling pathway, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Calcium signaling pathway, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

IHC 1:100~200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TNNC1

https://www.ncbi.nlm.nih.gov/gene/?term=7134

https://www.uniprot.org/uniprot/P63316