Cardiale Troponine T (TNNT2) Muismonoklonale Antilichaam [Kloon ID: LBI3C6]

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM) . [provided by RefSeq, Jul

Carrier-free (BSA/glycerol-free) TNNT2 mouse monoclonal antibody, clone LBI3C6

CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC

Homo sapiens troponin T2, cardiac type (TNNT2), transcript variant 1, mRNA.

7139

P45379

Unconjugated

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TNNT2

https://www.ncbi.nlm.nih.gov/gene/?term=7139

https://www.uniprot.org/uniprot/P45379