Cardiale Troponine T (TNNT2) Muismonoklonale Antilichaam [Kloon ID: UMLBI205]

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. (provided by RefSeq, Jul 2008)

Carrier-free (BSA/glycerol-free) Troponin T (TNNT2) mouse monoclonal antibody, clone UMLBI205

CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC

Homo sapiens troponin T2, cardiac type (TNNT2), transcript variant 1, mRNA.

7139

P45379

Unconjugated

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

IHC 1:100~200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TNNT2

https://www.ncbi.nlm.nih.gov/gene/?term=7139

https://www.uniprot.org/uniprot/P45379