CARF Antilichaam - C-terminalgebied: Biotine (ARP40869_T100-Biotine)

CDKN2A interacting protein

CARF

55602

Q9NXV6

NP_060102

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human CARF

CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.

UBC; XRN2; RPA3; RPA2; RPA1; WHSC1; VCP; Cdkn2a; MDC1; BRCA1; BARD1; GGH; EPHX1; MDM2; CUL3; SUMO2; RAD21; DHX58; Clp1

Biotin

Polyclonal Antibody

WB, IHC

CDKN2AIP is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

64kDa

Hasan, M.K., (2002) J. Biol. Chem. 277 (40), 37765-37770

Wet Ice

580

CDKN2AIP

CDKN2AIP

Rabbit

CDKN2A-interacting protein

NM_017632

AIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKS