CARS Antilichaam

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.

833

P49589

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 469-748 of human CARS (NP_001742.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 85kDa

IgG

CARS

HeLa

BxPC-3

MCF7

Mouse liver

Mouse skeletal muscle

Cysteinyl-tRNA synthetase

Homo sapiens

CARS, CARS1, CYSRS, MGC:11246

WB, IHC, IF

Liquid