Cartilage Oligomeric Matrix Protein (COMP), Monoklonale Antilichaam (Clone 15A11)

This antibody binds to the fourth EGF (Epithelial Growth Factor) -like domain of mouse COMP, comprising residues 232–252, called the P6 epitope. Cartilage Oligomeric Matrix Protein (COMP) is a disulfide-linked pentameric proteoglycan primarily found in cartilage, but also present in other joint tissues such as meniscus, tendon, synovial fibroblasts, and osteoblasts. As a member of the thrombospondin family, COMP stimulates type II collagen fibril formation. It is released into the blood when cartilage is damaged, making it a valuable biomarker for predicting cartilage destruction in inflammatory joint diseases like rheumatoid arthritis (RA) and osteoarthritis (OA) .

This antibody binds to the fourth EGF (Epithelial Growth Factor) -like domain of mouse COMP, comprising residues 232–252, called the P6 epitope. Cartilage Oligomeric Matrix Protein (COMP) is a disulfide-linked pentameric...

Cartilage Oligomeric Matrix Protein (COMP), Monoclonal Antibody (Clone 15A11), 100ug

Mouse, Rat, Human

Rat COMP

15A11

Immunohistochemistry (IHC), in-vivo functional assays.

Antibodies

It is recommended that the user determine the optimal dilution for their application. The typical starting working dilutions are for IHC 1:100.

This antibody is soluble and supplied in PBS.

Mouse IgG1, k