Cartilage Oligomeric Matrix Protein (COMP), Monoklonale Antilichaam (Clone 16B5)

This antibody binds to the coiled-coil domain or pentamer COMP. It cross-reacts with mouse, rat and human. Cartilage Oligomeric Matrix Protein (COMP) is a disulfide-linked pentameric proteoglycan primarily found in cartilage, but also present in other joint tissues such as meniscus, tendon, synovial fibroblasts, and osteoblasts. As a member of the thrombospondin family, COMP stimulates type II collagen fibril formation. It is released into the blood when cartilage is damaged, making it a valuable biomarker for predicting cartilage destruction in inflammatory joint diseases like rheumatoid arthritis (RA) and osteoarthritis (OA) .

This antibody binds to the coiled-coil domain or pentamer COMP. It cross-reacts with mouse, rat and human. Cartilage Oligomeric Matrix Protein (COMP) is a disulfide-linked pentameric proteoglycan primarily found in cartilage, ...

Cartilage Oligomeric Matrix Protein (COMP), Monoclonal Antibody (Clone 16B5), 100ug

Mouse, Rat, Human

Rat COMP

16B5

Immunohistochemistry (IHC), ELISA

Antibodies

It is recommended that the user determine the optimal dilution for their application. The typical starting working dilutions are for IHC 1:100, ELISA 1:200-1:500.

This antibody is soluble and supplied in PBS.

Mouse IgG1, k