CASP7 Antilichaam

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

840

P55210

Human, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human CASP7 (NP_001218.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

CASP7

Caspase 7, apoptosis-related cysteine peptidase

Homo sapiens

Caspase-7 Antibody: MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3, MCH3, Caspase-7, Apoptotic protease Mch-3

IHC, IP

Liquid