CASP7 Antilichaam - N-terminalgebied: FITC (ARP58995 P050-FITC)

Caspase 7, apoptosis-related cysteine peptidase

MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3

840

P55210

NP_203124

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

PTGES3; BAX; PARP1; SAT1; CRYAB; XIAP; RPS6KA1; CTSA; PEPD; MVD; GNS; GBP2; EEF2; CAPN1; CNDP2; GINS2; EIF4H; GZMB; ROCK1; DFFA; CASP9; CASP7; CASP3; ARHGDIA; VIM; STAT1; SPTAN1; CLSPN; PLA2G4B; RB1; UBC; BIRC2; CCT2; VCP; SP1; BIRC3; BIRC6; COPS6; TERF1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

CASP7 is supported by BioGPS gene expression data to be expressed in OVCAR3

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

37kDa

Wet Ice

336

CASP7

CASP7

Rabbit

Caspase-7

NM_033338

NNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLL