Caspase-13 Antilichaam

Caspase-13 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.

338039

O75601

O75601

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Apoptosis, Cancer

Caspase-13 Antibody is Ion exchange chromatography purified.

Cat. No. 1209 - HL60 Cell Lysate

1 mg/ml

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Caspase-13 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

Caspase-13 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

43 kDa

IgG

CASP4

Cat. No. 1403 - Mouse Brain Tissue Lysate

Cat. No. 1463 - Rat Brain Tissue Lysate

Caspase 4, apoptosis-related cysteine peptidase

Bos taurus

Humke EW, Ni J, Dixit VM. ERICE, a novel FLICE-activatable caspase. J Biol Chem 1998;273:15702-7 (WD0500)

Caspase-13 Antibody: CASP13, Caspase-13, Evolutionary related interleukin-1-beta-converting enzyme, CASP-13

ELISA, WB, IHC-P

10720034

Liquid