Caspase 9 Antilichaam [A7C3]

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

842

P55211

Human, Mouse

Recombinant protein of human Caspase 9

[A7C3]

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Affinity purification

C2C12

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 37kDa, 39kDa, 46kDa

IgG

CASP9

Caspase 9, apoptosis-related cysteine peptidase

Homo sapiens

Caspase-9 Antibody: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, MCH6, Caspase-9, Apoptotic protease Mch-6, CASP-9

WB, IHC, ICC, IF, IP

Liquid