Cassiatannine A

Cassiatannin A is a tetramer of proanthocyanidin found in Cinnamomum cassia. Cassiatannin A shows COX-2 inhibitor activity with inhibition rate of 38, 52 and 97% at 10, 100 and 1000 μg/mL. Cassiatannin A can be used for the research of inflammation[1].

1206883-80-8

12352005

COX

Immunology/Inflammation

Inflammation/Immunology

O[C@H]1[C@]2(C3=CC(O)=C(C=C3)O)OC4=C(C5=C([C@H](C6=C7C(C[C@@H]([C@@H](C8=CC(O)=C(C=C8)O)O7)O)=C(C=C6O)O)[C@H]([C@@H](C9=CC(O)=C(C=C9)O)O5)O)C(O)=C4[C@H]%10C%11=C(O)C=C(O)C=C%11O[C@H](C%12=CC(O)=C(C=C%12)O)[C@@H]%10O)[C@@]1([H])C%13=C(O)C=C(O)C=C%13O2

C60H48O24

1153.01

[1]Killday KB, et al. Bioactive A-type proanthocyanidins from Cinnamomum cassia. J Nat Prod. 2011 Sep 23;74 (9) :1833-41.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16482/

Natural Products

No Development Reported

COX-2