CAT-antilichaam

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

847

P04040

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human CAT (NP_001743.1) .

Unconjugated

Primary Antibodies

Cancer, Neuroscience, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 59kDa

IgG

CAT

293T

HepG2

Mouse kidney

Mouse liver

Rat kidney

Catalase

Homo sapiens

CAT, catalase, HGNC:1516, MGC138422, MGC138424

WB, IP

Liquid