(+) -Catechine-3-gallat

(+) -Catechin 3-gallate is an orally active polyphenolic compound that acts as a non-selective proteasome inhibitor. (+) -Catechin 3-gallate exerts antitumor effects by inducing apoptosis and suppressing inflammatory cytokines. (+) -Catechin 3-gallate is promising for research of cancers (e.g., breast, prostate) and neurodegenerative diseases (e.g., Alzheimer’s) [1].

25615-05-8

12352005

Proteasome

Metabolic Enzyme/Protease

Cancer-Kinase/protease

Cancer; Neurological Disease

O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@@H](C3=CC(O)=C(C=C3)O)OC4=CC(O)=CC(O)=C4C2

C22H18O10

442.37

[1]Haslam E. (+) -catechin-3-gallate and a polymeric proanthocyanidin from Bergenia species. J Chem Soc Perkin 1. 1969;14:1824-8.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16453/

Natural Products

No Development Reported