β-catenineremmende peptoïde
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2579070-02-1
Androgen Receptor, Wnt/beta-catenin
Endocrinology/Hormones, Cytoskeletal Signaling, Stem Cells
β-catenin inhibitory peptoid (compound 13) disrupts the interaction between β-catenin and TCF with an IC50 of 5.44 μM. It inhibits Wnt signaling in prostate cancer cell lines (IC50 = 0.105 μM) and androgen receptor (AR) signaling (IC50 = 1.02 μM) . This compound significantly reduces cell proliferation in prostate cancer cell lines.
O=C1N(CC(=O)N(CCCOC(C)C)CC(=O)N([C@@H](C)C2=CC=C(OC)C=C2)CC(=O)N([C@@H](C)C3=CC=C(OC)C=C3)CC(=O)N[C@H](C)C(=O)N(CCC4=C(OC5=CC=CC=C5)C=CC=C4)C1)C6=CC(OC)=CC(OC)=C6
C59H72N6O12
1057.24
Ice Packs
-20°C
Beschrijving
β-catenineremmende peptoïde Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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