Cathepsine E substraat e

Cathepsin E substrate e is a substrate of Cathepsin E. Cathepsin E substrate e was designed in such a way that due to the close proximity of a Mca-donor and a Dnp-acceptor, a near complete intramolecular quenching effect was achieved in its intact state. After the proteolytic cleavage of the hydrophobic motif of the peptide substrate, both Mca and Dnp would be further apart, resulting in bright fluorescence[1].

1246741-19-4

12352209

Cathepsin

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Others

O=C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CC(C1=CC=C(C=C1O2)OC)=CC2=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)CO)=O)CC(C)C)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](CCCNC(N)=N)C(N)=O)=O)CCCCNC5=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C5)=O)C)=O)CCC4

C61H82N16O18

1327.40

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10922/

Peptides

No Development Reported