Caveoline 1 (CAV1) Mouse Monoclonal Antibody [Kloon ID: LBI2C4]

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. [provided by RefSeq, Mar 2010]

Carrier-free (BSA/glycerol-free) CAV1 mouse monoclonal antibody, clone LBI2C4

BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21

Homo sapiens caveolin 1 (CAV1), transcript variant 1, mRNA.

857

Q03135

Unconjugated

Focal adhesion, Viral myocarditis

Focal adhesion, Viral myocarditis

WB 1:500, IHC 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CAV1

https://www.ncbi.nlm.nih.gov/gene/?term=857

https://www.uniprot.org/uniprot/Q03135