Caveoline 2 (fosfo Tyr27) Antilichaam

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.

858

P51636

NP_001224.1

Human

Caveolin 2 (phospho Tyr27) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y (p) -A-D) derived from Human Caveolin 2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

26 kDa

IgG

The antibody detects endogenous levels of Caveolin 2 only when phosphorylated at tyrosine 27.

Western Blot: 1:500~1:1000

CAV2

Caveolin 2

Homo sapiens

Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135 (1996) .

Scherer P.E., J. Biol. Chem. 272:29337-29346 (1997) .

Engelman J.A., FEBS Lett. 448:221-230 (1999) .

CAV2, Caveolin-2

WB

4557413

Liquid