CAY10734
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CAY10734 is the agonist for sphingosine-1-phosphate receptor 1 (S1P1) with an IC50 of 1.3 nM. CAY10734 promotes the recirculation of peripheral blood lymphocytes, and is a potential immunosuppressant[1].
635701-59-6
12352005
H302-H315-H319-H335
LPL Receptor
GPCR/G Protein
Inflammation/Immunology
O=C(O)C1CN(C1)CC2=CC=C(C=C2)C3=NOC(C4=CC=C(CC(C)C)C=C4)=N3
C23H25N3O3
391.46
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Li Z, et al., Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3. J Med Chem. 2005 Oct 6;48 (20) :6169-73.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-50692/
Reference compound1
No Development Reported
Beschrijving
CAY10734 is the agonist for sphingosine-1-phosphate receptor 1 (S1P1) with an IC50 of 1.3 nM. CAY10734 promotes the recirculation of peripheral blood lymphocyte
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