CAZIP-antilichaam

CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1) -dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.

23281

Q5JR59

NP_001028774

Human, Mouse

Unconjugated

Primary Antibodies

Homeostasis

CAZIP Antibody is affinity chromatography purified via peptide column.

Cat. No. 1288 - A20 Cell Lysate

1 mg/mL

CAZIP Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CAZIP antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

MTUS2

Microtubule associated tumor suppressor candidate 2

Homo sapiens

Du Puy L, Beqqali A, Monshouwer-Kloots J, et al. CAZIP, a novel protein expressed in the developing heart and nervous system. Dev. Dyn.2009; 238:2903-11.

Jiang K, Wang J, Liu J, et al. TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep.2009; 10:857-65.

CAZIP Antibody: ICIS, CAZIP, TIP150, KIAA0774, Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Tracking protein of 150 kDa

ELISA, WB, IHC-P, IF

140161498

Liquid