CB-103
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Orally active inhibitor of the Notch signaling activation complex (IC50’s from 0.9 to 3.9 µM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with γ-secretase Notch inhibitors.
Unconjugated
Off-white to pale orange solid
RT
Beschrijving
CB-103 Beschikbaar in 20 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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