CBFA2T2 Antilichaam - middengebied: FITC (ARP38559_P050-FITC)

Core-binding factor, runt domain, alpha subunit 2; translocated to, 2

EHT, p85, MTGR1, ZMYND3

9139

O43439

NP_005084

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human CBFA2T2

In acute myeloid leukemia, especially in the M2 subtype, the t (8;21) (q22; q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-

PRDM14; PDP1; CBFA2T2; TCP1; MDFI; RUNX1T1; LBP; APP; ATXN1L; ATN1; RERE; RUNX1; SIN3A; NCOR1; HDAC3; FBXL19; TAL2; NEUROG1; ID3; GTF2E1; WDYHV1; CBFA2T3; NCOR2; CBFB; TAL1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

67kDa

Lyberopoulou, A., (2007) Cell. Physiol. Biochem. 20 (6), 995-1006

Wet Ice

604

CBFA2T2

CBFA2T2

Rabbit

Protein CBFA2T2

NM_013277

GQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNG