CBX1 Antilichaam - middelste regio : HRP (ARP34427 T100-HRP)

Chromobox homolog 1

CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta

10951

P83916

NP_006798

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human CBX1

CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM].

PRDM6; SUMO1; UBC; RNF2; PARK2; NR2F6; VHL; EHMT2; ABI3BP; VTN; TRIM39; CBX5; HIST1H3B; KLF11; HIST3H3; PCNA; MECP2; ADNP; POGZ; ADNP2; CBX3; TRIM28; CHAF1A; HIST1H4F; XRCC6; CHD4; H2AFB1; NSL1; SUMO2; HIST1H3A; Mad2l2; Cbx1; DNMT3B; ZNF382; H3F3A; SUV420

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Verschure, P.J., et al., (2005) Mol. Cell. Biol. 25 (11), 4552-4564

Wet Ice

185

CBX1

CBX1

Rabbit

Chromobox protein homolog 1

NM_006807

PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP