CBX5 Antilichaam

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

23468

P45973

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CBX5 (NP_001120794.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 22kDa

IgG

CBX5

Jurkat

SH-SY5Y

A-549

MCF7

Mouse brain

Chromobox homolog 5

Homo sapiens

CBX5, HP1, HP1A, HEL25

WB, IHC, IF

Liquid