CCAR1 Antilichaam - C-terminaal gebied: Biotine (ARP61069 P050-Biotine)

Cell division cycle and apoptosis regulator 1

CARP1, DIS

55749

Q8IX12

NP_060707.2

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCAR1

CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. It is recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. It also functions as a p53 coactivator. It may thus play an important role in transcriptional regulation (By similarity) . It may be involved in apoptosis signaling in the presence of the reinoid CD437. It apoptosis induction involves sequestration of 14-3-3 protein (s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. And it plays a role in cell cycle progression and/or cell proliferation.

PIH1D3; GOLGA2; SUMO2; SUMO3; UBC; TP53; MDM2; U2AF2; CHERP; UBL4A; RBM10; RNF113A; HNRNPK; SMURF1; BARD1; SIRT7; SF3A2; Kif23; FYCO1; CASP10; SFN; YWHAQ

Biotin

Polyclonal Antibody

WB

Affinity purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

126 kDa

Wet Ice

1150

CCAR1

CCAR1

Rabbit

Cell division cycle and apoptosis regulator protein 1

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