CCL14 / HCC-1 / HCC-3 Protein (aa 28-93, His Tag)

CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona) . CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5) . Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14 promote trophoblast migration.

CC-1 Protein; CC-3 Protein; CKB1 Protein; HCC-1 Protein; HCC-1 (1-74) Protein; HCC-1/HCC-3 Protein; HCC-3 Protein; MCIF Protein; NCC-2 Protein; NCC2 Protein; SCYA14 Protein; SCYL2 Protein; SY14 Protein

Q16627-1

Human

Human

His-Tag

See Datasheet send with the product

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> 95 % as determined by SDS-PAGE

Data not available

77

Lyophilized

PBS, pH 7.4

See Datasheet send with the product

9.3 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

E.coli