CCL2 / MCP-1 / MCP1 Proteïne (Zijn label)

Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.

GDCF-2 Protein; HC11 Protein; HSMCR30 Protein; MCAF Protein; MCP-1 Protein; MCP1 Protein; MGC9434 Protein; SCYA2 Protein; SMC-CF Protein

NP_002973.1

Human

Human

His-Tag

See Datasheet send with the product

Please contact us for more information.

> 95 % as determined by SDS-PAGE

Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with mouse CCR2. The ED50 for this effect is 20-200 ng/mL.

86

Lyophilized

PBS, pH 7.4

See Datasheet send with the product

10.1 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Yeast