CCL21/6Ckine Proteïne

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 21 (CCL21), also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine (SLC), is a small cytokine belonging to the C-C chemokine family. CCL21 takes its name 6Ckine for its consititutively six conserved cysteine residues but not four cysteines typical to chemokines. CCL21 has function in ininducing vigorous calcium migrations and chemotactic responses.

6Ckine Protein; CKb9 Protein; ECL Protein; exodus-2 Protein; SCYA21 Protein; SLC Protein; TCA4 Protein; UNQ784/PRO1600 Protein

O00585

Human

Human

See Datasheet send with the product

< 1.0 EU per μg of the protein as determined by the LAL method

> 98 % as determined by SDS-PAGE

Data not available

111

Lyophilized

40mM Tris, 0.3 M NaCl, pH 7.4

See Datasheet send with the product

12.3 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Insect cells