CCL21/6Ckine Proteïne (Zijn label)

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 21 (CCL21), also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine (SLC), is a small cytokine belonging to the C-C chemokine family. CCL21 takes its name 6Ckine for its consititutively six conserved cysteine residues but not four cysteines typical to chemokines. CCL21 has function in ininducing vigorous calcium migrations and chemotactic responses.

6CKBAC2 Protein; 6Ckine Protein; ALP Protein; CKb9 Protein; Gm1987 Protein; plt Protein; Scya21 Protein; SCYA21a Protein; Scya21b Protein; SLC Protein; Tca4 Protein

NP_035254.1

Mouse

Mouse

His-Tag

See Datasheet send with the product

< 1.0 EU per μg protein as determined by the LAL method.

> 95 % as determined by SDS-PAGE.

Data not available

121

Lyophilized

20 mM Tris, 300 mM NaCl, 10 % Glycerol, pH 8.0

See Datasheet send with the product

13.5 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Insect cells