CCR8-eiwit (N-Vlag & C-His, mens)

CCR8

CC-CKR-8, CCR-8, CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, GPRCY6, TER1

N-Flag & C-His

< 1.0 EU per μg protein as determined by the LAL method.

≥ 80 % as determined by SDS-PAGE.

1.Recombinant Human CCR8 Protein (Nanodisc, Flag & His Tag) (Cat: 11450-H18H-NA) at 5 μg/mL (100 μL/well) can bind BMS-986340-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1, the EC50 is 3-9 ng/mL (QC tested) . 2.Recombinant Human CCR8 Protein (Nanodisc, Flag & His Tag) (Cat: 11450-H18H-NA) at 5 μg/mL (100 μL/well) can bind S-531011-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1, the EC50 is 3-11 ng/mL (Routinely tested) . 3.Recombinant Human CCR8 Protein (Nanodisc, Flag & His Tag) (Cat: 11450-H18H-NA) at 5 μg/mL (100 μL/well) can bind JTX-1811-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1, the EC50 is 3.5-10.5 ng/mL (Routinely tested) . 4.BMS-986340-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1 captured on Protein A chip, can bind Recombinant Human CCR8 Protein (Nanodisc, Flag & His Tag) (Cat: 11450-H18H-NA) with an affinity constant of 2.810 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

Met1-Arg227 & Asn232-Ser318

The recombinant Human CCR8 comprises 396 amino acids and predicts a molecular mass of 45.13 kDa. As a result of glycosylation, it migrates as an approximately 102.8 and 43.5 kDa band in SDS-PAGE under reducing conditions.

Human