
CCT-010354
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CCT-010354 is a PPARα/δ dual agonist. CCT-010354’s EC50 on PPAR α and PPAR δ are 26.5 nM and 25.7 nM. CCT-010354 can be used for the study of cholestatic liver disease[1].
32549-31-8
12352005
H302
PPAR
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Inflammation/Immunology
O=C1NC(CN1C2=CC=C(C)C=C2)=O
C10H10N2O2
190.20
P264-P270-P330-P501
[1]Feng Z, et al. Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases. J Med Chem. 2023 Jun 8;66 (11) :7331-7354.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W318305/
Reference compound2
No Development Reported
PPARα; PPARδ
Beschrijving
CCT-010354 is a PPARα/δ dual agonist. CCT-010354’s EC50 on PPAR α and PPAR δ are 26.5 nM and 25.7 nM. CCT-010354 can be used for the study of cholestatic liver
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