CCT7 Antilichaam - middengebied: FITC (ARP51808 P050-FITC)

Chaperonin containing TCP1, subunit 7 (eta)

CCTH, CCTETA, NIP7-1, TCP1ETA

10574

Q99832

NP_006420

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human CCT7

CCT7 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.

SSSCA1; TP53; FUS; HUWE1; NEDD1; UBC; TUBG1; SUMO2; LGALS3BP; CDC20; MDM2; WWOX; ASB7; CCT3; CCT6A; PRPF40A; CCT5; CCT8; CCT2; CCT4; FBXO6; UBD; FBXW4; BAG3; HDAC6; HDAC3; ILK; CDK5; CDK2; AICDA; PAN2; METTL21B; VCAM1; FAM86B2; METTL18; PEX14; NOS2; NKX3-

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB, IHC

Affinity Purified

CCT7 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 93%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

60kDa

Guo, D., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1308-1318

Wet Ice

543

CCT7

CCT7

Rabbit

T-complex protein 1 subunit eta

NM_006429

RAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPR

Eta