CD10-antilichaam [2A1H5E1]

CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA) . It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

4311

P08473

P08473

Human

Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3) .

2A1H5E1

Unconjugated

Primary Antibodies

Signal Transduction

Antibody is purified by protein G affinity chromatography.

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

CD10 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2b

MME

Membrane metallo-endopeptidase

Homo sapiens

Sato Y, et.al. Journal of Gastroenterology,1996 Feb.31 (1) :12-7.

Inukai T, et.al. British Journal of Haematology,1995,89 (3) :623-6.

EPN, Atriopeptidase, CALLA, NEP, SFE, CD10

ELISA, IHC

128062